endo-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester

Name	N-Boc-endo-3-aminotropane
Synonyms	N-Boc-endo-3-aminotropane endo-3-Amino-8-Boc-8-azab... N-Boc-3-amino-8-azabicyclo[3.2.1]octane endo-3-Amino-8-Boc-8-azabicyclo[3.2.1]octane tert-Butyl endo-3-amino-8-azabicyclo[3.2.1]octane-8-carboxylate tert-butyl (1S,5R)-3-amino-8-azabicyclo[3.2.1]octane-8-carboxylate 1,1-DiMethylethyl 3-endo-aMino-8-azabicyclo[3.2.1]octane-8-carboxylate (1R,3s,5S)-rel-tert-Butyl 3-aMino-8-azabicyclo[3.2.1]octane-8-carboxylate endo-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester (3-endo)-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
CAS	207405-68-3

Molecular Formula	C12H22N2O2
Molar Mass	226.32
Density	1.084
Boling Point	313.2±35.0 °C(Predicted)
pKa	10.12±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

Uses	N-Boc-ne-3-aminotropane is a new conformationally defined bridged ring amino acid drug molecular block with a unique three-dimensional rigid structure. It is used as a new alternative of classic aliphatic nitrogen-containing heterocycles in the development and research of anti-hepatitis B virus drugs.
Preparation	Using (3-internal)-3-benzylamine-8-azabicyclo [3.2.1] octane-8-tert-butyl formate as the starting material, the target compound N-Boc-ne-3-aminotropane was prepared by palladium-carbon reduction. The synthesis reaction formula is as follows:

Last Update：2024-04-09 21:21:28

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CAS: 207405-68-3
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endo-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester Request for Quotation